Acetaminophen Side Effects



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Acetaminophen side effects may be serious. If you experience any of the following symptoms, call your doctor immediately:

  • rash
  • hives
  • itching
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing


  • It may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

    OVERDOSE
    Overdoses from this medication is one of the most common poisonings worldwide. People often think that just because it is a pain-relieving medicine it must be extremely safe. However, it may be deadly if taken in large doses.

    Overdose Symptoms:

  • Abdominal pain
  • Appetite loss
  • Coma
  • Convulsions
  • Diarrhea
  • Irritability
  • Nausea
  • Sweating
  • Upset stomach
  • Vomiting

  • Note: Symptoms may not occur until 12 or more hours after the pills were swallowed.

    Check with your doctor as soon as possible if any of the following side effects occur:

    RARE SIDE EFFECTS:

  • Bloody or black, tarry stools
  • Bloody or cloudy urine
  • Fever with or without chills (not present before treatment and not caused by the condition being treated)
  • Pain in lower back and/or side (severe and/or sharp)
  • Pinpoint red spots on skin
  • Skin rash, hives, or itching
  • Sores, ulcers, or white spots on lips or in mouth
  • Sore throat (not present before treatment and not caused by the condition being treated)
  • Sudden decrease in amount of urine
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness


  • Taking certain other medicines together with acetaminophen may increase the chance of unwanted effects. The risk will depend on how much of each medicine you take every day, and on how long you take the medicines together. If your medical doctor or dentist directs you to take these medicines together on a regular basis, follow his or her directions carefully. However, do not take any of the following medicines together with acetaminophen for more than a few days unless your doctor has directed you to do so and is following your progress:

  • Aspirin or other salicylates
  • Diclofenac (e.g., Voltaren)
  • Diflunisal (e.g., Dolobid)
  • Etodolac (e.g., Lodine)
  • Fenoprofen (e.g., Nalfon)
  • Floctafenine (e.g., Idarac)
  • Flurbiprofen, oral (e.g., Ansaid)
  • Ibuprofen (e.g., Motrin)
  • Indomethacin (e.g., Indocin)
  • Ketoprofen (e.g., Orudis)
  • Ketorolac (e.g., Toradol)
  • Meclofenamate (e.g., Meclomen)
  • Mefenamic acid (e.g., Ponstel)
  • Nabumetone (e.g., Relafen)
  • Naproxen (e.g., Naprosyn)
  • Oxaprozin (e.g., Daypro)
  • Phenylbutazone (e.g., Butazolidin)
  • Piroxicam (e.g., Feldene)
  • Sulindac (e.g., Clinoril)
  • Tenoxicam (e.g., Apo-Tenoxicam)
  • Tiaprofenic acid (e.g., Surgam)
  • Tolmetin (e.g., Tolectin)
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    ...less medical jargon in a 'Quick Glance' format!